Medical balloon

ABSTRACT

A non-compliant medical balloon, where the non-compliant medical balloon may be changed from a deflated state to an inflated state by increasing pressure within the balloon, is made with a first fiber layer, a second fiber layer over said first fiber layer such that the fibers of the first fiber layer and the fibers of the second fiber layer form an angle and a binding layer coating the first fiber layer and said second fiber layer. The interior surface area of the non-compliant medical balloon remains unchanged when the balloon changes from a deflated state to an inflated state.

FIELD OF THE INVENTION

This invention relates to the field of balloons that are useful in angioplasty and other medical uses.

BACKGROUND OF THE INVENTION

Catheters having inflatable balloon attachments have been used for reaching small areas of the body for medical treatments, such as in coronary angioplasty and the like. Balloons are exposed to large amounts of pressure. Additionally, the profile of balloons must be small in order to be introduced into blood vessels and other small areas of the body. Therefore, materials with high strength relative to film thickness are chosen. An example of these materials is PET (polyethylene terephthalate), which is useful for providing a non-compliant, high-pressure device. Unfortunately, PET and other materials with igh strength-to-film thickness ratios tend to be scratch- and puncture-sensitive. Polymers that tend to be less sensitive, such as polyethylene, nylon, and urethane are compliant and, at the same film thickness as the non-compliant PET, do not provide the strength required to withstand the pressure used for transit in a blood vessel and expansion to open an occluded vessel. Non-compliance, or the ability not to expand beyond a predetermined size on pressure and to maintain substantially, a profile, is a desired characteristic for balloons so as not to rupture or dissect the vessel as the balloon expands. Further difficulties often arise in guiding a balloon catheter into a desired location in a patient due to the friction between the apparatus and the vessel through which the apparatus passes. The result of this friction is failure of the balloon due to abrasion and puncture during handling and use and also from over-inflation.

The present invention is directed to a non-compliant medical balloon suitable for angioplasty and other medical procedures and which integrally includes very thin inelastic fibers having high tensile strength, and methods for manufacturing the balloon. The fiber reinforced balloons of the present invention meet the requirements of medical balloons by providing superior burst strength; superior abrasion-, cut- and puncture-resistence; and superior structural integrity.

More particularly, the invention is directed to a fiber-reinforced medical balloon having long axis, wherein the balloon comprises an inner polymeric wall capable of sustaining pressure when inflated or expanded into a fiber/polymeric matrix outer wall surrounding and reinforcing the inner polymeric wall. The fiber/polymeric matrix outer wall is formed from at least two layers of fibers and a polymer layer. The fibers of the first fiber layer are substantially equal in length to the length of the long axis of the balloon and run along the length of the long axis. But “substantially equal in length” is meant that the fiber is at least 75% as long as the length of the long axis of the balloon, and preferably is at least 90% as long. The fiber of the second fiber layer runs radically around the circumference of the long axis of the balloon substantially over the entire length of the long axis. By “substantially over the entire length” is meant that the fiber runs along at least the center 75% of the length of the long axis of the balloon, and preferably runs along at least 90% of the length. The fiber of the second fiber layer is substantially perpendicular to the fibers of the first fiber layer. By “substantially perpendicular to” is meant that the fiber of the second fiber layer can be up to about 10 degrees from the perpendicular.

The invention is further directed to processes for manufacturing a non-compliant medical balloon. In one embodiment, a thin layer of a polymeric solution is applied over a mandrel, the mandrel having the shape of a medical balloon and being removable from the finished product. High-strength inelastic fibers are applied to the thin layer of polymer with a first fiber layer having fibers running substantially along the length of he long axis of the balloon and a second fiber layer having fiber running radially around the circumference of the long axis substantially over the entire length of the long axis. The fibers are then coated with a thin layer of a polymeric solution to form a fiber/polymeric matrix. The polymers are cured and the mandrel is removed to give the fiber-reinforced medical balloon.

In another embodiment of the invention, a polymer balloon is inflated and is maintained in its inflated state, keeping the shape of the balloon. High-strength inelastic fibers are applied to the surface of the balloon, with a first fiber layer having fibers running substantially along the length of the long axis of the balloon and a second fiber layer having fiber running radially around the circumference of the long axis substantially over the entire length of the long axis. The fibers are then coated with a thin layer of a polymeric solution to form a fiber/polymeric matrix. The fiber/polymeric matrix is cured to give the fiber-reinforced medical balloon, which can then be deflated for convenience, until use.

In a presently preferred embodiment, a thin coating of an adhesive is applied to the inflated polymer balloon or to the polymer-coated mandrel prior to applying the inelastic fibers.

BRIEF DESCRIPTION OF THE DRAWINGS

FIG. 1 illustrates an inflated standard medical balloon, which is used in the invention as the base of the final composite fiber-reinforced balloon.

FIG. 2 illustrates an inflated standard medical balloon, which is used in this invention as the base of the final composite fiber-reinforced balloon.

FIG. 3 illustrates the positioning of the second layer of fiber over the first fiber layer. The fiber is wound radially around the long axis substantially over the entire length of the long axis of the balloon, each wrap being substantially equally spaced from the others. The fiber runs substantially perpendicular to the fibers of the first fiber layer.

FIG. 4 illustrates the positioning of the third layer of fiber over the second fiber layer, in accordance with another embodiment.

DETAILED DESCRIPTION OF THE INVENTION

Referring now to the drawings, wherein like reference numbers are used to designate like elements throughout the various views, several embodiments of the present invention are further described. The figures are not necessarily drawn to scale, and in some instances the drawings have been exaggerated or simplified for illustrative purposes only. One of ordinary skill in the art will appreciate the many possible applications and variations of the present invention based on the following examples of possible embodiments of the present invention.

A medical balloon in accordance with the present invention in one embodiment begins with an inflated polymeric balloon 2, as shown in FIG. 1, to which there is applied by hand or mechanically, inelastic fiber or filament 4, as shown in FIG. 2. This is sometimes referred to as the “primary wind.” To assist in placement and retention of the fibers, there can be applied an adhesive to either the inflated balloon surface or to the fiber. The purpose of this first application of fiber is to prevent longitudinal extension (growth) of the completed balloon.

An alternate method of applying the longitudinal fibers involves first creating a fabric of longitudinal fibers by pulling taut multiple parallel fibers on a flat plate and coating with a polymeric solution to create a fabric. The fabric is then cut into a pattern such that it can be wrapped around the base balloon or mandrel.

Next, a second application of inelastic fiber 6 is applied to the circumference of the balloon, as shown in FIG. 3. This is sometimes referred to as the “hoop wind.” The purpose of the hoop wind is to prevent or minimize distension of the completed balloon diameter during high inflation pressures.

After the hoop wind is completed, the exterior of the fiber-wound inflated balloon is coated with a polymeric solution and cured to form a composite, con-compliant fiber-reinforced medical balloon. The outer polymeric coating of the fiber/polymeric matrix secures and bonds the fibers to the underlying inflated balloon so that movement of the fibers is restricted during deflation of the composite balloon and subsequent inflation and deflation during use of the balloon. The polymeric solution can be applied several times, if desired. The polymeric solution can use the same polymer as or a polymer different from the polymer of the inflated polymeric balloon 2. The polymers should be compatible so that separation of the composite balloon is prevented or minimized.

In a second method of making a medical balloon of the present invention, a removable mandrel having the shape that is identical to the shape of the inside of the desired balloon is used. A shape such as shown in FIG. 1 is suitable. The mandrel can be made of collapsible metal or polymeric bladder, foams, waxes, low-melting metal alloys, and the like. The mandrel is first coated with a layer of a polymer, which is then cured. This forms the inner polymeric wall of the balloon. Next, repeating the steps as described above, the primary wind and the hoop wind are placed over the inner polymer wall, followed by a coating with a polymeric solution and curing thereof to form a fiber/polymeric matrix outer wall. Finally, the mandrel is removed, by methods known in the art such as by mechanical action, by solvent, or by temperature change, to give the composite medical balloon of the invention.

In view of the high strength of the balloons of the present invention, it is possible to make balloons having a wall thickness less than conventional or prior art balloons without sacrifice of burst strength, abrasion resistence, or puncture resistance. The balloon wall thickness can be less than the thickness given in the examples hereinbelow.

In addition, the fiber-reinforced balloons of the present invention are non-complaint. That is, they are characterized by minimal axial stretch and minimal radial distention and by the ability not to expand beyond a predetermined size on pressure and to maintain substantially a profile.

Polymers and copolymers that can be used for the base balloon and/or the covering layer of the fiber/polymeric matrix include the conventional polymers and copolymers used in medical balloon construction, such as, but not limited to, polyethylene, polyethylene terephthalate (PET), polycaprolactam, polyesters, polyethers, polyamides, polyurethanes, polyimides, ABS copolymers, polyester/polyether block copolymers, ionomer resins, liquid crystal polymers, and rigid rod polymers.

The high-strength fibers are chosen to be inelastic. By “inelastic,” as used herein and in the appended claims, is meant that the fibers have very minimal elasticity or stretch. Zero elasticity or stretch is probably unobtainable taking into account the sensitivity of modern precision test and measurement instruments, affordable costs and other factors. Therefore, the term “inelastic” should be understood to mean fibers that are generally classified as inelastic but which, nevertheless, may have a detectable, but minimal elasticity or stretch. High strength inelastic fibers useful in the present invention include but are not limited to; Kevlar, Vectran, Spectra, Dacron, Dyneema, Terlon (PBT), Zylon (PBO), Polyimide (PIM), ultra high molecular weight polyethylene, and the like. In a presently preferred embodiment, the fibers are ribbon-like; that is, they have a flattened to a rectangular shape. The fibers of the first fiber layer may be the same as or different from the fiber of the second fiber layer.

The most advantageous density of the fiber wind is determinable through routine experimentation by one of ordinary skill in the art given the examples and guidelines herein. With respect to the longitudinally-placed fibers (along the long axis of the balloon) of the first fiber layer, generally about 15 to 30 fibers having a fiber thickness of about 0.0005 to 0.001 inch and placed equidistant from one another will provide adequate strength for a standard-sized medical balloon. With respect to the fiber of the hoop wind, or second fiber layer, fiber having a thickness of about 0.0005 to 0.001 inch and a wind density within the range of about 50 to 80 wraps per inch is generally adequate. The fiber of the second fiber layer is preferably continuous and is, for a standard-sized medical balloon, about 75-100 inches long.

The longitudinally placed fibers should be generally parallel to or substantially parallel to the long axis of the balloon or maximum longitudinal stability (non-stretch) of the balloon. The fibers of the hoop wind should be perpendicular to or substantially perpendicular to the fibers placed longitudinally for maximum radial stability (non-stretch) of the balloon. This distributes the force on the balloon surface equally and creates “pixels” of equal shape and size. In the case where the fibers of the hoop wind are at a small acute angle (e.g. about 10 degrees or more) to the longitudinal fibers, two hoop winds (in opposite direction) can be used for minimizing radial distention. FIG. 4 depicts a balloon having a second hoop wind 12.

EXAMPLES

The following examples are provided to illustrate the practice of the present invention, and are intended neither to define nor to limit the scope of the invention in any manner.

Example 1

An angioplasty balloon, as shown in FIG. 1, having a wall thickness of 0.0008 inch is inflated to about 100 psi, and the two open ends of the balloon are closed off. The inflation pressure maintains the shape (geometry) of the balloon in an inflated profile during the construction of the composite balloon. The balloon is a blow-molded balloon of highly oriented polyethylene terephthalate (PET). To the inflated balloon is applied a very thin coat of 3M-75 adhesive to hold the fibers sufficiently to prevent them from slipping out of position after placement on the balloon.

Kevlar® fibers are placed, by hand, along the length of the balloon as shown in FIG. 2 to provide the primary wind. Each of the fibers is substantially equal in length to the length of the long axis of the balloon. Twenty-four fibers are used, substantially equally spaced from each other. The fiber used for the primary wind has a thickness of 0.0006 inch.

Next, a hoop wind of Kevlar® fiber is applied radially around the circumference of and over substantially the entire length of the long axis of the balloon, as shown in FIG. 3. The fiber has a thickness of 0.0006 inch and is applied at a wind density of 60 wraps per inch.

The fiber-wound based PET balloon is then coated with a 10% solution of Texin® 5265 polyurethane in dimethylacetamide (DMA) and allowed to cure at room temperature. Five additional coating of the polurethane solution are applied in about 6-hour increments, after which the pressure in the balloon is released. The resulting composite fiber-reinforced balloon is non-compliant and exhibits superior burst strength and abrasion and puncture resistance.

3M-75 is a tacky adhesive available from 3M Company, Minneapolis, Minn. Kevlar® is a high strength, inelastic fiber available from the DuPont Company, Wilmington, Del. Texin® 5265 is a polyurethane polymer available from Miles, Inc., Pittsburgh, Pa.

Example 2

The procedure of Example 1 was repeated with the exception that Vectran® fiber, having a thickness of 0.0005 inch is used in place of the Kevlar® fiber. The resulting composite balloon is axially and radially non-compliant at very high working pressures. The balloon has a very high tensile strength and abrasion and puncture resistance.

Vectran® is a high strength fiber available from Hoechst-Celanese, Charlotte, N.C.

Example 3

A mandrel in the shape of a balloon as shown in FIG. 1 is made of a water-soluble wax. The wax mandrel is coated with a very thin layer (0.0002 inch) of Texin® 5265 polyurethane. After curing, adhesive and Vectran® fibers are applied, following the procedure of Example 1. Next, several coats of Texin® 5265 polyurethane as applied in Example 1. The wax is then exhausted by dissolving in hot water to give a non-compliant, very high strength, abrasion-resistant, composite fiber-reinforced balloon.

Example 4

The procedure of Example 3 is repeated using high strength Spectra® fiber in place of Vectran® fiber. Spectra® fiber is available from Allied Signal, Inc., Morristown, N.J.

Example 5

The procedure of Example 1 is repeated using Ultra High Molecular Weight Polyethylene (Spectra 2000) fiber, which has been flattened on a roll mill. To the flattened fiber is applied a thin coat of a solution of 1-MP Tecoflex® adhesive in a 60-40 solution of methylene chloride and methylethylketone. The fiber is applied to the balloon as in Example 1 using 30 longitudinal fibers, each substantially equal in length to the length of the long axis of the balloon, and a hoop wind of 54 wraps per inch. The fibers are then coated with the Tecoflex® solution.

Tecoflex® is supplied by Thermedics, Inc., Woburn, Mass.

Example 6

A balloon-shaped solid mandrel made of a low melting temperature metal alloy is coated with a thin layer of Texin® 5265/DMA solution (10%). Vectran® fibers are applied as in Example 1, followed by coating with Texin®/DMA. The metal mandrel is melted out using hot water. A very high strength, abrasion-resistant, composite balloon is obtained, which is non-compliant.

Example 7

Following the procedures of Example 6, a mandrel is coated with a very thin layer of PIM polyimide (2,2-dimethylbenzidine) in solution in cyclopentanone. Polyimide fibers are applied, and the composite balloon is then completed with additional applications of the PIM solution. The mandrel is removed to give a high strength, puncture-resistant balloon having an extremely cohesive fiber/matrix composite wall that is resistant to delamination.

Example 8

A balloon is constructed as in Example 7, except that the longitudinal fibers are replaced by a longitudinally oriented thin film made of polyimide LARC-1A film (available from IMITEC, Schenectady, N.Y.). The film is cut into a mandrel-shaped pattern and applied to the mandrel, over which the polyimide hoop fibers and the PIM solution are applied.

Although the illustrative embodiment has been described in detail, it should be understood that various changes, substitutions and alterations can be made therein without departing from the spirit and scope of the invention as defined by the appended claims. 

1-17. (canceled)
 18. A medical balloon having opposing ends, comprising: a first reinforcement layer having lower elasticity in a first direction than in a second direction, the second direction forming an angle with respect to the first direction within the first reinforcement layer, the opposing ends aligning with the first direction; and a second reinforcement layer bonded to the first reinforcement layer, the second reinforcement layer having lower elasticity in the second direction than in the first direction within the second reinforcement layer.
 19. The balloon as in claim 18, further comprising an adhesive layer between the first and second reinforcement layers.
 20. The balloon as in claim 18, the first reinforcement layer including a polymer with a plurality of elongate reinforcement members attached thereto, the elongate reinforcement members aligning with the first direction.
 21. The balloon as in claim 18, the first reinforcement layer including a polymer with a plurality of elongate reinforcement members attached thereto, the elongate reinforcement members aligning with the first direction.
 22. The balloon as in claim 18, the first reinforcement layer including a polymer with an elongate reinforcement member attached thereto, the elongate reinforcement member of the first reinforcement layer aligning with the first direction; and the second reinforcement layer including a polymer with a plurality of elongate reinforcement members, the elongate reinforcement members of the second reinforcement layer aligning with the second direction and forming a helix.
 23. The balloon as in claim 18, the first reinforcement layer including a polymer with a plurality of elongate reinforcement members adhesively attached thereto, the plurality of elongate reinforcement members aligning with the first direction.
 24. The balloon as in claim 18, the first reinforcement layer including a polymer with a plurality of elongate flattened reinforcement fibers attached thereto, the plurality of elongate flattened reinforcement fibers aligning with the first direction.
 25. The balloon as in claim 18, the balloon when inflated having a longitudinal shape having a longitudinal axis, the first reinforced layer including a polymer with a plurality of elongate reinforcement members, the plurality of elongate reinforcement members aligning with the longitudinal axis.
 26. The balloon as in claim 18, the first reinforcement layer including a polymer with a plurality of elongate reinforcement members, the plurality of elongate reinforcement members including at least one of Kevlar, Vectran, Spectra, Dacron, Dyneema, Terlon (PBT), Zylon (PBO), Polyimide (PIM), and ultra high molecular weight polyethylene.
 27. The balloon as in claim 18, the first reinforcement layer including a layer of polymer including at least one of polyethylene, polyethylene terephthalate (PET), polycaprolactam, polyester, polyether, polyamide, polyurethane, polyimide, ABS copolymer, polyester/polyether block copolymer, ionomer resin, liquid crystal polymer, and rigid rod polymer, the first reinforcement layer further including a plurality of elongate reinforcement members including at least one of Kevlar, Vectran, Spectra, Dacron, Dyneema, Terlon (PBT), Zylon (PBO), Polyimide (PIM), and ultra high molecular weight polyethylene.
 28. The balloon as in claim 18, the second reinforcement layer including a layer of polymer with at least one elongate reinforcement member helically wound about the balloon.
 29. The balloon as in claim 18, the first reinforcement layer including a base layer of at least one of polyethylene, polyethylene terephthalate (PET), polycaprolactam, polyester, polyether, polyamide, polyurethane, polyimide, ABS copolymer, polyester/polyether block copolymer, ionomer resin, liquid crystal polymer, and rigid rod polymer, the base layer being overlaid with an oriented film adhesively bonded thereto.
 30. A medical balloon, comprising: a polymeric wall capable of sustaining pressure when inflated; at least a portion of the wall having first and second layers bonded together, each layer having an elasticity in an inelastic direction that is less than an elasticity in an elastic direction, the elastic direction being at approximately a right angle to the inelastic direction; the first layer inelastic direction forming an acute or right angle with respect to the second layer inelastic direction.
 31. The balloon as in claim 30, the first layer being continuous along a first side of the second layer.
 32. The balloon as in claim 30, at least a portion of the first layer and at least a portion of the second layer defining respective cylinders with the first layer cylinder being inside the second layer cylinder.
 33. The balloon as in claim 30, when the balloon is inflated, the wall defining a cylindrical shape with an axis, and the first layer inelastic direction being parallel to the axis.
 34. The balloon as in claim 30, when the balloon is inflated, the wall defining a cylindrical shape with an axis, and the second layer inelastic direction being perpendicular to the axis.
 35. The balloon as in claim 30, at least one of the first and second layers including tensile reinforcing filaments having orientations determining the at least one of the first and second layer inelastic directions.
 36. The balloon as in claim 30, the first layer including at least one of polyethylene, polyethylene terephthalate, polycaprolactam, polyester, polyether, polyamide, polyurethane, polyamide, ABS copolymer, polyester/polyether block copolymer, ionomer resin, liquid crystal polymer, and rigid rod polymer.
 37. The balloon as in claim 30, the first layer including at least one of Kevlar, Vectran, Spectra, Dacron, Dyneema, Terlon (PBT), Zylon (PBO), Polyimide (PIM), and ultra high molecular weight polyethylene.
 38. The balloon as in claim 30, the first and second layers being reinforced composites with inelastic components oriented in the respective inelastic directions of each layer.
 39. A medical balloon, comprising: an inner polymeric wall capable of sustaining pressure when inflated or expanded and a polymeric reinforcing wall surrounding the inner polymeric wall; the polymeric reinforcing wall having at least first and second layers, each layer having low elasticity in a direction; the first layer direction being approximately parallel to a balloon axis extending between opposing ends of the balloon; the second layer direction being disposed around the balloon axis.
 40. The balloon as in claim 39, the first layer including a plurality of elongate reinforcement members attached thereto.
 41. The balloon as in claim 39, the first layer including a plurality of elongate reinforcement members adhesively attached thereto.
 42. The balloon as in claim 39, the first layer including a plurality of reinforcement fibers attached thereto.
 43. The balloon as in claim 39, the first layer including a plurality of reinforcement fibers attached thereto.
 44. The balloon as in claim 39, the first layer including a plurality of reinforcement fibers oriented approximately parallel to the first layer direction.
 45. The balloon as in claim 39, the first and second layers each including reinforcement fibers oriented approximately parallel to the first and second layer directions, respectively.
 46. The balloon as in claim 39, the first layer including a plurality of elongate reinforcement members including at least one of Kevlar, Vectran, Spectra, Dacron, Dyneema, Terion (PBT), Zylon (PBO), Polyimide (PIM), and ultra high molecular weight polyethylene.
 47. The balloon as in claim 39, the first layer including at least one of polyethylene, polyethylene terephthalate (PET), polycaprolactam, polyesters, polyether, polyamide, polyurethane, polyimide, ABS copolymer, polyester/polyether block copolymer, ionomer resin, liquid crystal polymer, and rigid rod polymer, the first layer further including a plurality of elongate reinforcement members including at least one of Kevlar, Vectran, Spectra, Dacron, Dyneema, Terlon (PBT), Zylon (PBO), Polyimide (PIM), and ultra high molecular weight polyethylene.
 48. The balloon as in claim 39, the second layer including at least one elongate reinforcement member forming a helix.
 49. The balloon as in claim 39, the first layer including a base layer of at least one of polyethylene, polyethylene terephthalate (PET), polycaprolactam, polyester, polyether, polyamide, polyurethane, polyimide, (ABS copolymer, polyester/polyether block copolymer, ionomer resin, liquid crystal polymer, and rigid rod polymer, the base layer overlaid with an oriented film adhesively bonded thereto.
 50. A medical balloon, comprising: a wall having a first layer of oriented material providing greater tensile strength in a longitudinal direction than in a circumferential direction; the wall having a second layer of oriented material adjacent the first layer, the second layer providing greater tensile strength in the circumferential direction than in the longitudinal direction; the first and second layers being continuous and bonded together, the first layer being on a side of the second layer for an entirety of the wall.
 51. The balloon as in claim 50, the wall defining a cylindrical shape when the balloon is inflated, with an axis aligned with the longitudinal direction.
 52. The balloon as in claim 50, at least one of the first and second layers including tensile reinforcing fibers.
 53. The balloon as in claim 50, the first layer including at least one of polyethylene, polyethylene terephthalate, polycaprolactam, polyester, polyether, polyamide, polyurethane, polyamide, ABS copolymer, polyester/polyether block copolymer, ionomer resin, liquid crystal polymer, and a rigid rod copolymer.
 54. The balloon as in claim 50, the first layer icluding at least one of Kevlar, Vectran, Spectra, Dacron, Terlon (PBT), Zylon (PBO), Polyimide (PIM), and ultra high molecular weight polyethylene.
 55. The balloon as in claim 50, the first and second layers being reinforced composites with components providing the tensile strength of the oriented material in the respective directions.
 56. A medical balloon, comprising: a wall having a first layer of oriented material minimizing a longitudinal extension of the balloon when inflated under pressure, the first layer providing greater tensile strength in a longitudinal direction than in another direction orthogonal to the longitudinal direction; the wall having a second layer of oriented material bonded to the first layer, the second layer providing greater tensile strength in the another direction than in the longitudinal direction; the first layer extending to fully cover a side of the second layer.
 57. The balloon as in claim 56, further comprising a binding layer between the first and second layers maintaining the angle between the longitudinal and another directions when expanding the balloon.
 58. The balloon as in claim 56, at least one of the first and second layers being a composite structure including high strength tensile elements minimizing longitudinal extension.
 59. The balloon as in claim 56, at least one of the first and second layers including at least one of polyethylene, polyethylene terephthalate, polycaprolactam, polyester, polyether, polyamide, polyurethane, polyamides (ABS copolymer, polyester/polyether block copolymer, ionomer resin, liquid crystal polymer, and rigid red polymer.
 60. The balloon as in claim 56, the first and second layers including at least one of Kevlar, Vectran, Spectra, Dacron, Dyneema, Terlon (PBT), Zylon (PBO), Polyamide (PIM), and ultra high molecular weight polyethylene. 